The breakout moment in Debra Messing's career came with her iconic role as Grace Adler in the NBC sitcom "Will & Grace." Premiering in 1998, the show became a groundbreaking series, particularly for its positive portrayal of LGBTQ+ characters. Messing's portrayal of Grace, an endearing and quirky interior designer, earned her widespread recognition and critical acclaim. Her impeccable comedic timing and chemistry with co-stars, including Eric McCormack, contributed significantly to the show's success. Messing received several award nominations for her role, including an Emmy Award in 2003 for Outstanding Lead Actress in a Comedy Series.